We report the case of a 48-year-old, Caucasian female who presented with slowly progressing asymptomatic poikilodermatous changes of the extensor aspects of the forearms.She also had typical Poikiloderma of Civatte on the V of the neck and erythemato-telangiectatic rosacea of the central face.The patient had been practicing aroma-therapy for many U
Functional Connectivity Density with Frequency-Dependent Changes in Patients with Diffuse Axonal Injury: A Resting-State Functional Magnetic Resonance Imaging Study
Guojin Xia,1,2 Zhenzhen Hu,3 Fuqing Zhou,1,2 Wenfeng Duan,1,2 Min Wang,1,2 Honghan Gong,1,2 Yulin He,1,2 Yanxing Guan4 1Department of Radiology, The First Affiliated Glasses Hospital of Nanchang University, Jiangxi, People’s Republic of China; 2Jiangxi Province Medical Imaging Research Institute, Jiangxi, People’s Republic of China; 3De
Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions
AT-rich interactive domain 1A (ARID1A) has emerged as a new tumor suppressor in which frequent somatic mutations have been identified in several types of human cancers.Although most ARID1A somatic mutations are frame-shift or nonsense mutations that contribute to mRNA decay and loss of protein expression, 5% of ARID1A mutations are in-frame inserti